HIV-1 Protease with Inhibitor

Entry retrieved from the Protein Data Bank at RCSB.

1A8G: Complex (Acid Proteinase Inhibitor). Date: Mar 24, 1998.
Title:Hiv-1 Protease In Complex With Sdz283-910
Authors: S.Ringhofer, J.Kallen, R.Dutzler, A.Billich, A.Visser, D.Scholz, O.Steinhauser, H.Schreiber, M.Auer, A.Kungl
Compound: Hiv-1 Protease with Inhibitor Sdz283-910.
Method: X-Ray Diffraction. Resolution: 2.5 Ang.
Ligands: CBZ (CARBOBENZOXY GROUP), HV5 (TERT-BUTYLALANINE), HV8 (BENZYL-2-AMINO-PARAMETHOXY-BENZYLSTATINE), HV7 (1-METHYLAMINE-2-HYDROXY-4-METHOXY-BENZENE).

The protease is displayed as "ribbons" and the color is selected so as to emphasize the "chain" structure.


Figure. The X-ray structure of HIV-1 protease with inhibitor Sdz283-910.