Tetracycline

Entry retrieved from the Protein Data Bank at RCSB.

2TRT: Transcription Regulation. Date: Mar 04, 1994.
Title: Tetracycline Repressor Class D
Authors: W.Hinrichs, C.Kisker, M.Duvel, A.Muller, K.Tovar, W.Hillen, W.Saenger.
Molecule: Tetracycline Repressor Class D. Source: Escherichia Coli.
Method: X-Ray Diffraction. Resolution: 2.5 Ang. Ligand: TAC (Tetracycline), MG (magnesium dication).

Use the ChemFinder to find out about the excat structure of tetracycline. Tetracycline functions as an antibiotioc because this substance interferes with translation. Tetracycline prevents the aminoacetyl-tRNA from binding to the ribosome.


Figure. The X-ray structure of tetracycline bound to a tetracycline repressor protein.