 |
 |
||
| Other Names | (±)-4-[1-hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-butyl]-alpha,alpha-dimethyl benzeneacetic acid hydrochloride | Other Names | Edifas B; Sodium carboxymethyl cellulose |
| Molecular Formula | C32H40ClNO4 | Molecular Formula | C28H30Na8O27 |
| CAS # | 138452-21-8 | CAS # | 9004-32-4 |
| NOWRAP>Molecular Weight (g) | 538.1253 | Molecular Weight (g) | 982.4470 |
| Physical State & Appearance | White to off white powder | Physical State & Appearance | White to off white powder |
| Melting Point (ºC) | Unavailable | Melting Point (ºC) | >300 |
| Boiling Point (ºC) | Unavailable | Boiling Point (ºC) | >300 |
| Density (g/mL) | Unavailable | Density (g/mL) | .75 |
| Solubility in Water | Slight | Solubility in Water | Slight to soluble |
| Other Solubilities | Freely soluble in methanol and ethanol, slightly soluble in chloroform, insoluble in hexane | Other Solubilities | Insoluble in organic liquids |
| Origin | Synthetic | Origin | Synthetic |
| Method of Isolation | Metabolism of terfenadine | Method of Isolation | Manufactured from cellulose which has been processed to have a high affinity for water. |
| Intended Function | Antihistamine with selective peripheral H1-receptor antagonist activity. | Intended Function | Dissolution accelerator--a "super" disintegrant because it is very effective even at low concentrations at promoting the breakdown of tablets following ingestion. |
 |
 |
||
| Other Names | Octadecanoic Acid; Magnesium Salt | Other Names | MCC; Cellulose |
| Molecular Formula | C36H70MgO4 | Molecular Formula | (C6H10O5)n |
| CAS # | 557-04-0 | CAS # | 9004-34-6 |
| Molecular Weight (g) | 591.2516 | Molecular Weight (g) | 160,000-560,000 |
| Physical State & Appearance | Fine, white to yellow-white powder | Physical State & Appearance | Fine, white to off white, crystalline powder |
| Melting Point (ºC) | 150-170 | Melting Point (ºC) | Varies depending on molecular weight |
| Boiling Point (ºC) | Unavailable | Boiling Point (ºC) | Decomposes |
| Density (g/mL) | 1.02 | Density (g/mL) | Unavailable |
| Solubility in Water | Insoluble | Solubility in Water | Insoluble |
| Other Solubilities | Insoluble in ether; soluble in hot alchohol | Other Solubilities | Unavailable |
| Specific Gravity | 1.03 | Vapor Pressure | 0 mm Hg (approx.) |
| Origin | Natural | Origin | Natural |
| Method of Isolation | Magnesium salt of stearic acid | Method of Isolation | Acid hydrolysis of fibrous cellulose |
| Intended Function | Lubricant that reduces wear and friction on equipment during the tablet process and aids in enhancing the flow properties of the powders during mixing. | Intended Function | It serves multiple functions. Particularly, it is an excellent binder and disentegrant. |
 |
 |
||
| Other Names | Amglogen | Other Names | Hydroxy propyl methyl cellulose; 2-hydroxy propyl methyl ether cellulose |
| Molecular Formula | (C6H10O5)n | Molecular Formula | C56H108O30 |
| CAS # | 9005-25-8 | CAS # | 9004-65-3 |
| Molecular Weight (g) | Varies due to molecular weight | Molecular Weight (g) | 1261.4512 |
| Physical State & Appearance | Fine, white solid | Physical State & Appearance | White to off white powder |
| Melting Point (ºC) | Decomposes | Melting Point (ºC) | Decomposes at 220 |
| Boiling Point (ºC) | Decomposes | Boiling Point (ºC) | n/a |
| Density (g/mL) | 1.5 | Viscosity | 50-50,000 cps (2% sol.) |
| Solubility in Water | Insoluble | Solubility in Water | Swells to form viscosity colloidal solution. |
| Other Solubilities | Unavailable | Other Solubilities | Soluble in most organic solvents; insoluble in hot water and alcohol |
| Origin | Natural | Origin | Natural |
| Method of Isolation | Derived from corn | Method of Isolation | Derived from cellulose |
| Intended Function | It is primarily a binding agent used to improve tablet durability and integrity but is also used as a disentigrant. After ingestion, starch granules swell in the fluid environment of the stomach and force the tablet to break apart. | Intended Function | It helps protect the tablet's integrity and aids in the ease of swallowing the tablets. It is also a constituent of the film-coating agent used on tablets. |
 oxide.gif) |
 |
||
| Other Names | Because Iron (iii) oxide is the primary component in these blends, all data provided is for this compound. | Other Names | PEG; Macrogol; Polyoxyethylene; Aquaffin |
| Molecular Formula | Fe2O3 | Molecular Formula | H(OCH2)nOH |
| CAS # | 1332-37-2 | CAS # | 25322-68-3 |
| Molecular Weight (g) | 159.6882 | Molecular Weight (g) | Varies |
| Physical State & Appearance | Reddish brown powder | Physical State & Appearance | Clear to white semi-solid |
| Melting Point (ºC) | 1538-1565 | Melting Point (ºC) | 65 |
| Boiling Point (ºC) | Unavailable | Boiling Point (ºC) | Unavailable |
| Density (g/mL) | 5.24-5.25 | Density (g/mL) | 1.101 |
| Solubility in Water | Insoluble | Solubility in Water | Soluble |
| Other Solubilities | Unavailable | Other Solubilities | Insoluble in DMSO and ethanol |
| Origin | Iron oxide is natural; blend is sythetic. | Origin | Synthetic |
| Method of Isolation | Unavailable | Method of Isolation | Esterfication of ethylene glycol |
| Intended Function | It is used as a coloring agent. | Intended Function | It is an anti-redeposition agent, an emulsifying agent, and a water-soluble lubricant. |
 |
 |
||
| Other Names | 1-ethenyl-2-pyrrolidinone; Polyvinylpyrrolidone K-30 | Other Names | Free crystalline silica; Sand; Fumed silica |
| Molecular Formula | (C6H9NO)n | Molecular Formula | O2Si |
| CAS # | 9003-39-8 | CAS # | 14808-60-7 |
| Molecular Weight (g) | 10,000 avg. | Molecular Weight (g) | 60.0848 |
| Physical State & Appearance | White or creamy white powder | Physical State & Appearance | Colorless solid |
| Melting Point (ºC) | 225 (Varies with molecular weight) | Melting Point (ºC) | 1710 |
| Boiling Point (ºC) | Depends on molecular weight (may decompose upon heating). | Boiling Point (ºC) | 2230 |
| Density (g/mL) | Unavailable | Density (g/mL) | 2.2-2.6 |
| Solubility in Water | Soluble | Solubility in Water | Insoluble |
| Other Solubilities | Soluble in organic solvents | Other Solubilities | Unavailable |
| Specific Gravity | 1.23-1.29 | Specific Gravity | 2.66 |
| Origin | Unavailable | Origin | Natural |
| Method of Isolation | Unavailable | Method of Isolation | Hydrolysis of silicon tetrachloride with water and then heating the hydrated oxide that is formed. |
| Intended Function | It is a dispersing agent to provide colloid stability, a controlled release agent, a binder, a stabilizer, and a film former. | Intended Function | It promotes the flow of tableting powders and prevents them from sticking to the tablet presses. It promotes tablet disintegration and prevents caking. |
unavailable either does not apply or could not be found. |
|||
 |
|||
| Other Names | Titanium oxide; Tioxide; Atlas White Titanium Dioxide | ||
| Molecular Formula | O2Ti | ||
| CAS # | 13463-67-7 | ||
| Molecular Weight (g) | 79.8658 | ||
| Physical State & Appearance | White powder | ||
| Melting Point (ºC) | 1855-3000 | ||
| Boiling Point (ºC) | 2500-3000 | ||
| Density (g/mL) | 4.26 | ||
| Solubility in Water | Insoluble | ||
| pH | 7.5 | ||
| Specific Gravity | 3.9-4.2 | ||
| Origin | Natural | ||
| Method of Isolation | Derived from ilmenite or leuxocene ores | ||
| Intended Function | It is a pigment used for providing whiteness and opacity. | ||
This page optimized for 800x600 resolution.
Created by Rianna Myers as an Honors Project for Dr. Glaser's Winter '03 Chemistry 212 class at the University of Missouri-Columbia.